Last Updated: September 25, 2023


Leena Sanap


Programming languages form the core of a developer’s work. There are a variety of programming languages used for creating innovative products and applications. Among this variety, Python is one of the most preferred ones by coders.

Python Development Services are much in demand today as the language offers an array of applications from website design to the Graphical User Interface (GUI) framework.

The need for a GUI framework cannot be denied as the keyboard commands to elicit responses from a computer requires precise spelling. It creates problems as well as an unsuitable interface. To help developers resolve this problem, Python offers a wide range of GUI framework options for developers.

A Python GUI Library immensely assists the developers to expand their knowledge of its programming. In fact, one of the main reasons for its increasing popularity is the presence of many cross-platform libraries and frameworks.

It can be challenging to find one Best Python GUI Library, as there are lots of them available.

1. Tkinter

It is the standard Python GUI Library and is well-known for being convenient and simple. Developers can take advantage of the variety of resources, reference materials, and codes that it makes available. Tkinter comes by default; thus, you don’t need to spend time installing it. It’s an open-source framework that can be accessed on the Unix and Windows platform. It makes the process of creating a GUI-based application in Python truly effortless.


Kivy is the Most Popular Python GUI Library for creating applications with intelligent user interfaces like multi-touch apps. Its toolkits contain more than 20 widgets which makes it one of the best libraries for developing robust commercial products. This framework runs on Windows, OS X, Linux, Android, Raspberry Pi, and iOS. It is event-driven and the most appropriate for game development purposes.



It is a cross-platform Python GUI library. It is essentially an open-source wrapper for GUI components in the wxWidgets cross-platform library and is implemented as a Python extension module. It allows for the creation of native applications for Unix, Mac OS, and Windows. wxPython programs are written in the Python language. Hence, they are easily understandable.


Composed in C++ and documented from Python, Libavg is an open-source platform for developing media-centric applications. It can be seen as the Most Popular Python GUI Library due to its comprehensive range of features. It is perfectly suited to modern graphic intensive application requirements as it supports thousands of display elements. Licensed under Lesser General Public License (LGPL), it supports Python version 2.7. This platform supports all the major touch driver models like Windows touch, TUIO, and Linux XInput.


Another Best Python GUI Library to create custom GUIs is PySimpleGUI. There are four actively developed ports of this library. They are Tkinter, Qt using Pyside 2, WxPython, and Remi. It only supports Python 3. This Python GUI Library offers ease of use and can also be customized. It also runs on Raspberry Pi. A combination of Python and PySimpleGUI to create visually appealing and engaging user interfaces.


For developing GUI applications, developers can take advantage of Pyforms, a cross-environment framework. It’s the latest Python GUI Library which enables developers to code advanced functionalities with less effort. Prototyping applications become a lot easier using this framework. Due to these reasons, it can also be seen as the Best Python GUI Library.


Another user-friendly GUI toolkit, Wax is a framework that eliminates the low-level aspects of wxPython. It provides developers with simple Python objects to create their GUI. Its enhanced features like ease of use impart it more value than wxPython. Wax GUI is implemented as a PY extension module native code.


PyQT framework assembles the Qt C++ cross-platform application framework as well as the cross-platform interpreted language Python. It consists of abstractions of network sockets, Unicode, threads, regular expressions, SVG, OpenGL, XML, SQL databases, an operational web browser, a help system, and a complete set of GUI widgets. It supports all platforms, including Windows, OSX, Linux, Android, and iOS.



Flexx is a Python toolkit that helps developers create web and desktop applications and export an app to a standalone HTML document. It makes use of browser technology; hence the library is small and readily available as well as easy to use. Through this library, it is easy to mix Python that runs on a server with that which runs on the browser. Developers should make sure that Python and PScript code are well separated from each other. It supports browsers like Firefox, Edge, and Chrome.

CEF Python

Founded by Czarek Tomczak, CEF Python is developed to provide Python bindings for Chromium Embedded Framework. It is mainly focused on facilitating embedded browser use cases in many third-party applications. You can use it for automated testing of web applications that have advanced efficiencies than Selenium web browser automation. It is because of CEF low-level programming APIs.

Apart from GUI libraries, Python has numerous libraries for data science projects too. That proves the versatility of Python. However, there is an ongoing debate about whether Python is better for data science or Java. If you are interested in reading that article, See Full Article.


Python is a versatile programming language that is being widely used for web development these days. The ones mentioned above are some of the best GUI frameworks that Python offers. Depending on your requirements, you can leverage the services of a Python Development Company to create diverse GUI applications.

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